Preimplantation Genetic Testing (PGT)
at Fertilite Center in Tijuana, Mexico
We offer Preimplantation Genetic Testing (PGT) to ensure the health of your embryos before IVF transfer. This cutting-edge screening technique allows us to detect genetic abnormalities, giving you a clearer picture of embryo health and increasing the chances of a successful pregnancy. PGT helps minimize the risk of inherited conditions, making it an invaluable tool for improving IVF outcomes and reducing the likelihood of genetic disorders.
At Fertilite Center, our expert team provides compassionate, personalized care throughout the PGT process, guiding you in making the best decisions for your fertility journey and your family’s future.
What is Preimplantation Genetic Testing (PGT)?
Preimplantation Genetic Testing (PGT) is designed to assure you that your embryos are as healthy as possible before IVF transfer. This personalized service focuses on screening for genetic conditions, helping you make informed decisions that maximize the chances of a healthy pregnancy and the family you envision. This cutting-edge genetic screening technique allows us to select gender and detect potential genetic abnormalities in embryos, giving you a clearer understanding of their health before implantation
With a focus on your specific needs and fertility goals, PGT enhances the chances of a successful pregnancy while minimizing the risk of passing on inherited genetic conditions. Our expert team guides you through every step of the process, providing compassionate care and personalized support to ensure you’re making the most informed decisions for your family’s future conditions.
We offer the following types of PGT
PGT-A (Screening for Aneuploidies)
Fertilite Center offers PGT-A (Screening for Aneuploidies) as part of our personalized approach to IVF, designed to give you the best chance of a successful pregnancy. PGT-A is a state-of-the-art genetic screening that tests embryos for chromosomal abnormalities. By selecting embryos with optimal chromosomal health, we aim to eliminate the risks of failed implantation, miscarriage, or genetic disorders. Our compassionate team is dedicated to guiding you through each step of this process, providing expert care and personalized support to ensure the best possible outcome for you and your growing family.
PGT-M (Preimplantation Genetic Testing for Monogenic Disorders)
At Fertilite Center, we offer PGT-M (Preimplantation Genetic Testing for Monogenic Disorders) as a personalized service to help you make informed decisions about your family’s future. PGT-M is an advanced genetic screening technique used during IVF to detect specific single-gene (monogenic) disorders in embryos before implantation.
PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements)
We offer PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements) as part of our commitment to providing personalized fertility care. These advanced screening techniques help detect potential genetic concerns in embryos, from single-gene disorders to structural chromosomal abnormalities, giving you the information needed to make informed decisions. By selecting embryos without genetic or structural issues, we enhance your chances of a healthy pregnancy while minimizing the risk of miscarriage or developmental challenges. Our compassionate team is here to provide personalized guidance every step of the way, supporting you in creating the family you’ve dreamed of.
How PGT Works?
Consultation
Meet with our Fertilite doctor to discuss your medical history and how PGT fits into your IVF treatment plan.
Ovarian stimulation
Take hormonal injections to produce multiple eggs
Egg retrieval
Eggs are retrieved and fertilized in an IVF lab.
Embryo culture
Grow the embryos in a laboratory until they reach the blastocyst stage, typically on day 5 or 6
Embryo biopsy
Remove a few cells from each embryo. The biopsy is taken from the trophectoderm, which is the pre-placenta and will develop into the placenta.
Genetic testing
Send the biopsied cells to a lab for genetic testing.
Freeze embryos
Freeze the embryos until the results are available, which usually takes 7–10 days
Transfer embryos
prepare the embryos and transfer them to the woman in a subsequent cycle.
FAQ’s About PGT
PGT testing is available for most females undergoing IVF and it is often recommended for those with:
- A family history of genetic disorders: This includes disorders like cystic fibrosis, Huntington's disease, sickle cell anemia, muscular dystrophy, and hemophilia.
- A history of miscarriages: This could be due to chromosomal abnormalities or other reasons.
- Unexplained infertility: This could include multiple failed IVF cycles or other fertility challenges.
-Higher ages: This is because the risk of abnormal embryo genetics increases with age.
- A chromosomal translocation: This can cause implantation failure, recurrent pregnancy loss, or birth defects.
Most miscarriages are caused by chromosomally abnormal embryos. A PGT-A test helps identify embryos with normal chromosome numbers for successful implantation.
The decision to pursue genetic testing depends on various factors, including your age, genetic background, and medical history. Ultimately, PGT can enhance the chances of pregnancy for those undergoing IVF. It provides valuable insights into which embryos may lead to miscarriage or abnormal pregnancies, giving you greater control over your experience and your family’s health.
No, the PGT biopsy does not harm the embryo. Only a small number of cells are taken from an area that will later develop into the placenta, while the inner cell mass, which will become the baby, is left untouched.
PGT-M is recommended when a parent or a family member carries a genetic abnormality. This test can be performed alongside PGT-A, and the results can also help select an embryo of a specific sex. It is commonly used by patients who are carriers of sex-linked genetic disorders.
Preimplantation Genetic Testing (PGT) provides several important benefits, particularly for individuals or couples undergoing in vitro fertilization (IVF). These benefits include increased pregnancy success rates, prevention of genetic disorders, reduced need for invasive prenatal testing, improved selection of embryos, greater control over family planning, help with recurrent pregnancy loss, benefits for older maternal age, and increased viability for IVF patients with male factor infertility
No, PGT (Preimplantation Genetic Testing) is not the same as genetic testing during pregnancy. While both involve analyzing genetic material to identify abnormalities or conditions, they differ in timing, purpose, methods, and how they are performed.
Preimplantation genetic testing for monogenic disorders (PGT-M) can screen for many genetic conditions, including:
- Single-gene disorders: Cystic fibrosis, sickle cell anemia, Tay-Sachs disease, Huntington's disease, muscular dystrophy, thalassemia, hemophilia, and fragile X syndrome
- Cancer syndromes: BRCA1 and BRCA2 mutations, which are associated with breast and ovarian cancer
- Hereditary hemoglobinopathies: Autosomal recessive disorders that can be screened for with PGT-M
- X-linked disorders: Duchenne muscular dystrophy, hemophilia, and fragile X syndrome
- Other conditions: Marfan syndrome and Lynch syndrome
Yes, there are some risks associated with preimplantation genetic testing (PGT), including the risk of embryo damage, inaccurate test results, and emotional strain. Individuals and couples need to understand these potential risks before deciding to proceed.
Getting started with Preimplantation Genetic Testing (PGT) involves several steps, guided by fertility specialists and genetic counselors. By working closely with a fertility clinic and a genetic counselor, you can navigate the process of PGT with confidence and clarity.